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Page Title: Gonads (Testes and Ovaries)
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endocrine  portion  of  the  pancreas  consists  of  cells arranged   in   groups,   called   “islands   (islets)   of Langerhans.” The   islands   (islets)   of   Langerhans contain three types of endocrine cells: alpha, beta, and delta. The  alpha cells  secrete the hormone glucagon. Glucagon   causes   a   temporary   rise   in   blood   sugar levels. The beta cells secrete insulin, which is essential for  carbohydrate  metabolism.   Insulin   lowers  blood sugar levels by increasing tissue utilization of glucose and stimulating the formation and storage of glycogen in   the   liver.   Together,   glucagon   and   insulin   act   to regulate  sugar  metabolism  in  the  body.   Delta  cells produce   the   hormone   somatostatin.   Somatostatin helps   regulate   carbohydrates   by   inhibiting   the secretion of glucagon. When   the   islet   cells   are   destroyed   or   stop functioning,   the   sugar   absorbed   from   the   intestine remains in the blood and excess sugar is excreted by the  kidneys  into  the  urine.  This  condition  is  called diabetes   mellitus,   or   sugar   diabetes.   Insulin,   a synthetic  hormone,  is  given  to  patients  having  this disease as part of their ongoing treatment. GONADS (TESTES AND OVARIES) The term  gonads  refers to the primary sex organs of the reproductive system (male and female). Testes The  male  gonad  is  the  testis  (pl.  testes),  and  the existence   of   the   testes   is   the   primary   male   sex characteristic   (fig.   1-47).   The   testes   produce   and secrete   the   male   hormone    testosterone,   which influences  the  development  and  maintenance  of  the male   accessory   sex   organs   and   the   secondary   sex characteristics  of  the  male.  The  male  accessory  sex organs  include two groups of organs: the internal sex organs and the external sex organs. See section titled “Male Reproductive System” for more information on the male accessory sex organs. Male Secondary Sex Characteristics Male secondary sex characteristics influenced by the hormone testosterone are as follows: ·   Increased growth of hair, particularly in the areas of the face, chest, axilla, and pubic region. ·   Enlargement of the larynx (Adam's apple) and thickening of the vocal cords, which produces a lower-pitched voice. ·   Thickening of the skin. ·   Increased   muscle   growth,   broadening   of   the shoulder and narrowing of the waist. ·   Thickening and strengthening of the bones. Ovaries The   female   gonads,   the   ovaries,   produce   the hormones  estrogen  and  progesterone   (fig. 1-47). E s t r o g e n   i n f l u e n c e s   t h e   d e v e l o p m e n t   a n d maintenance  of  the  female  accessory  sex  organs a n d   t h e   s e c o n d a r y   s e x   c h a r a c t e r i s t i c s ,   a n d promotes changes in the mucous lining of the uterus ( e n d o m e t r i u m )   d u r i n g   t h e   m e n s t r u a l   c y c l e . Progesterone prepares the uterus for the reception and   development   of   the   fertilized   ovum   and maintains the lining during pregnancy. Today,   progesterone   and   estrogen   hormones (naturally   derived)   are   incorporated   into   oral contraceptives or birth control pills. The combination of hormones released through this monthly series of pills fools the body into not preparing (building-up of uterine lining) for implantation of an embryo. Because the   uterus   has   not   prepared   for   implantation, pregnancy cannot occur. Female accessory sex organs are also divided into internal and external accessory sex organs. See section titled   “Female   Reproductive   System”   for   more information on the female accessory sex organs. Female Secondary Sex Characteristics Female  secondary  sex  characteristics  influenced by the hormone estrogen are listed below. ·   Development   of   the   breasts   and   the   ductile system   of   the   mammary   glands   within   the breasts. ·   Increased quantities of fatty (or adipose) tissue in   the   subcutaneous   layer,   especially   in   the breasts, thighs, and buttocks. ·   Increased vascularization of the skin. 1-44

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