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Page Title: DISEASES OF THE GENITOURINARY (GU) TRACT
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DISEASES OF THE CIRCULATORY SYSTEM

radiate from side to side in the lower back. The pain often worsens when the patient is in a supine position  and  is  relieved  by  sitting  and  leaning forward.  Nausea  and  vomiting  as  well  as  con- stipation   are   common.   Bowel   sounds   may   be diminished, and the abdomen is usually distended. The   upper   abdomen   is   tender   with   muscle guarding   and   rebound   tenderness.   Fever, tachycardia,   shock,   pallor,   profuse   sweating with   cool,   clammy   skin,   and   jaundice   are common. TREATMENT—Give  the  patient  nothing  by mouth.  Place  on  complete  bed  rest.  Meperidine may  be  administered  for  pain.  DO  NOT  give morphine.  Place  the  patient  on  fluid  and  antibiotic therapy,  and  provide  nasogastric  suction. DISEASES OF THE GENITOURINARY  (GU)  TRACT The following are some of the more commonly encountered  diseases  of  the  GU  tract. Pyelonephritis This  acute  diffuse,  often  bilateral  pyogenic infection  of  the  kidneys  normally  occurs  via  the ascending route, but may be spread through the bloodstream  during  bacteremia.  It  is  sometimes precipitated  by  tumors  or  obstruction.  Diabetes increases   the   likelihood   of   infection.   Mixed infections  are  common  after  instrumentation  or from  fecal  flora  obtained  from  the  skin  of  the peritoneum. SYMPTOMS—The  symptoms  may  at  times be absent or obscured by associated disease. The patient  usually  experiences  chills,  fever,  flank pain,  nausea,  and  vomiting.  The  patient  may complain of urgency and frequency of urination, and   the   urine   may   contain   pus   or   blood. Sometimes there is abdominal rigidity, or in the absence of rigidity, a tender enlarged kidney may be  palpated.  Costovertebral  tenderness  on  the affected  side  is  common. TREATMENT—Perform  C&S  and  routine urinalysis. Before the specific pathogen is identi- fied,   start   broad-spectrum   antibiotic   therapy. When  the  specific  organism  is  identified,  treat with  the  appropriate  drug.  Force  fluids  to maintain urinary output of 2 to 3 liters per day. Treat  symptomatically  for  pain. Cystitis This  is  a  bladder  infection  resulting  from pathogens  entering  the  bladder  via  the  ureter. Infection   may   result   from   trauma,   stones,   or inadequate  emptying  of  the  bladder. SYMPTOMS—Gross  hematuria,  frequency and  urgency  of  urination,  and  in  most  cases, dysuria are common. A C&S often shows  E. coli as  the  offending  agent. TREATMENT—Perform    routine    urinalysis and  C&S.  Treat  systemically  with  antibiotics. Prostatitis Prostatitis is an infection of the prostate gland. Bacteria often reach the gland via the bloodstream or  the  urethra.  It  is  commonly  associated  with urethritis  or  active  infection  of  the  lower  GU tract. SYMPTONS—They  include  perineal  pain, urethral discharge (copious amounts produced by palpation),   fever,   dysuria,   and   urgency   and frequency of urination. Palpation of the prostate shows  the  gland  to  be  enlarged,  tender,  and boggy. Chronic prostatitis may serve as a source of  recurrent  lower  GU  tract  infection. TREATMENT—Acute   prostatitis   should   be treated with sulfas, tetracycline, erythromycin, or ampicillin  until  C&S  indicates  the  antibiotic  of choice.  Do  not  massage  the  prostate.  Chronic prostatitis  should  be  treated  with  long-term antimicrobial  therapy.  Follow  up  with  weekly prostate  massage  to  promote  drainage. Epididymitis This  inflammation  of  the  epididymis  is caused by severe straining, catheterization, pros- tatitis,  or  instrumentation. SYMPTOMS—The  disease  is  characterized  by severe pain in the scrotum and rapid unilateral enlargement  of  the  scrotum,  with  a  marked tenderness   over   the   spermatic   cord   that   is relieved by lifting the testes. Pyuria, bacteriuria, and  leukocytosis  are  usually  present. TREATMENT—General   measures   consist of   supporting   the   scrotum   with   a   scrotal bridge   or   pillow,   sitz   baths,   rest,   sedation, 2-13

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