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Back PHARMACEUTICAL PREPARATIONS | Up Hospital Corpsman 3 & 2 - Intro Navy Nursing manual for hospital training purposes | Next PRACTICAL PHARMACY PROCEDURES |
Methods of Preparation
must be in a fine degree of subdivision. Label
suspensions with a Shake Well label.
USES: Suspensions are used for the ad-
ministration of oral medicaments, which have low
volubility in water or aqueous vehicles. Also,
suspensions are used for parenteral drugs and
ophthalmic solutions.
OINTMENTS
Ointments are semisolid,
fatty, or oily
preparations of medicinal substances of such con-
sistency as to be easily applied to the skin and
gradually liquefy or melt at body temperature.
Ointments vary in color according to their ingre-
dients. The base of an ointment is generally of
a greasy character, and the medicinal substances
combined with it are always intended to be in very
fine particles, uniformly distributed.
Methods of Preparation
Incorporation: The medicinal substances are
finely powdered, if necessary, and then they are
levigated into the fatty base, either in the mortar
or on the ointment tile.
Fusion: The fatty base is melted, then the
finely powdered ingredients are added and mixed
thoroughly. The solution is cooled so that the
base, now containing the medicinal substances,
returns to its natural state.
USES: Ointments have long been a preferred
form for the external application of medicinal
substances. In addition to the action of the
medicinal substances combined with them, the
fatty bases are emollient and protective in nature.
Example: Zinc Oxide Ointment
SUPPOSITORIES
They are solid bodies intended to introduce
medicinal substances into the various orifices of
the body. The ingredients are incorporated in a
base that melts at body temperature. They are of
the following types:
. Rectal
l Vaginal
. Urethral
8-17
Fusion method: The ingredients are added to
melted theobroma oil (cocoa butter), and the mix-
ture poured into the suppository mold. The mix-
ture is allowed to cool, and the suppositories are
removed from the mold.
Hand Method: The medicinal ingredient is
combined with theobroma oil, and the mixture
is triturated into a pliable mass. The mass is rolled
by hand into the shape of a cylinder and divided
into the required number of equal parts, which
are then formed into the desired shape.
USES: Suppositories are commonly used for
the local application of medicinal substances, as
in the treatment of hemorrhoids. Occasionally
suppositories are used in administering medicinal
substances when administration by mouth is not
practical.
CAPSULES
Capsules are gelatin shells containing solid or
liquid medicinal substances to be taken orally. The
most common type of capsule is that in which the
medicine, in the form of a dry powder, is enclosed
in transparent cases made of gelatin. They are in
sized universally designated by numbers: 5, 4, 3,
2, 1, 0, 00, 000. The number 5 has the capacity
of about 65 mg of aspirin powder and the 00
about 975 mg of the same substance. It should
be noted that only sizes 3 through 00 are available
through the Federal Stock System.
INCOMPATIBILITIES
An understanding of incompatibilities can save
the pharmacy technician valuable time in com-
pounding as well as ensure the therapeutic effi-
ciency of the products. Incompatibilities are
divided into three classes: therapeutic, physical,
and chemical.
THERAPEUTIC
This type of incompatibility occurs when
agents antagonistic to one another are prescribed
together. Such circumstances seldom occur, but
when they do it does not necessarily indicate a mo-
ment of forgetfulness on the part of the physi-
cian. Such agents may have been used together
in order for one agent to modify the activity of
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